Acquired deficiency of coagulation factor VII

Acquired deficiency of coagulation factor VII

Factor VII (FVII) is found in small amounts in plasma and has a very short half-life in circulation. FVII is vitamin K-dependently synthesized in the liver. As such, hepatopathies, vitamin K deficiency, or use of vitamin K antagonists is the cause of acquired deficiency. Other types of acquired FVII deficiencies are rare.1 Here we describe a case of acquired factor VII deficiency associated to ...

Jaundice and factor VII deficiency in newborn

Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tiss...

Factor VII verona coagulation disorder: double heterozygosis with an abnormal factor VII and heterozygous factor VII deficiency.

A family with a peculiar defect of factor VII is described. The propositi, a brother and sister, were born of a nonconsanguineous marriage and presented a mild to moderate bleeding tendency since childhood (epistaxis, excessive bleeding after tooth extraction). The coagulation pattern was characterized by a mildly prolonged prothrombin time, normal partial thromboplastin time, and normal Stypve...

Factor VII antibody-neutralizing material in hereditary and acquired factor VII deficiency.

S EDITOR MARIO BALDINI, Providence, R. I. BOOK REVIEW EDITOR STEPHEN H. ROBINSON, Boston, Mass. BLOOD The Journal of Hematology II Fi aicx STOHLMAN, Jn., Editor in Chief, Boston, Mass. ERNST R. JAirFE, Associate Editor New York, N. Y. WILLIAM DA .sI x , Founding Editor EDITORIAL BOARD Jom W. ATHENS, Salt Lake City, Utah MARIO BALDINI, Providence, R. I. ERNEST BEIJTLER, Duarte, Calif. DANE R. Bo...

Inherited factor VII deficiency